BDBM50092645 (R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamide::CHEMBL111201::L-796568::N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[4-(4-trifluoromethyl-phenyl)-thiazol-2-yl]-benzenesulfonamide::N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[3-(4-trifluoromethyl-phenyl)-thiazol-2-yl]-benzenesulfonamide::N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[4-(4-trifluoromethyl-phenyl)-thiazol-2-yl]-benzenesulfonamide

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2nc(cs2)-c2ccc(cc2)C(F)(F)F)cc1)c1cccnc1

InChI Key: InChIKey=MSOUIIHPMJCUNI-UHFFFAOYSA-N

Data: 13 IC50  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50092645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Dog)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Rhesus macaque)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Rhesus macaque)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.430	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Rat)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Human)	BDBM50092645 (N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
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