BDBM50098785 4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-propyl]-piperidine::CHEMBL9653::UK-78282

SMILES COc1ccc(CCCN2CCC(COC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key InChIKey=WRTXEGOLODUQIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098785   

TargetPotassium voltage-gated channel subfamily A member 3(Mus musculus)
University of Kiel

Curated by ChEMBL
LigandPNGBDBM50098785(4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  280nMAssay Description:Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50098785(4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50098785(4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of human T-cells voltage-gated potassium channel subunit Kv1.3More data for this Ligand-Target Pair
In DepthDetails Article