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BDBM50102216 6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotinamide::CHEMBL294095

SMILES: CCS(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=GYTDPDSEJRDDCB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102216   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-8 receptors, CXCR2


(Homo sapiens (Human))
BDBM50102216
PNG
(6-Ethanesulfonyl-N-(4-fluoro-phenyl)-1-oxy-nicotin...)
Show SMILES CCS(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C14H13FN2O4S/c1-2-22(20,21)13-8-3-10(9-17(13)19)14(18)16-12-6-4-11(15)5-7-12/h3-9H,2H2,1H3,(H,16,18)
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UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Celltech R&D

Curated by ChEMBL


Assay Description
Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2


Bioorg Med Chem Lett 11: 1951-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00326-2
BindingDB Entry DOI: 10.7270/Q2TX3DN0
More data for this
Ligand-Target Pair