BDBM50103558 CHEMBL3357999

SMILES C[C@@H]1CN(CCN1c1ncc(OCc2ccc(cc2F)C#N)cn1)c1nnc(o1)C(F)(F)F

InChI Key InChIKey=DJPAKBMZZYZGIM-GFCCVEGCSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103558   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103558(CHEMBL3357999)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERG by patch clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103558(CHEMBL3357999)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50103558(CHEMBL3357999)
Affinity DataEC50:  216nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293S cells assessed as cAMP accumulation incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed