BDBM50105031 4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL324304

SMILES Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO

InChI Key InChIKey=ALQRUULAVXAWSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105031   

TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105031(4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyr...)
Affinity DataIC50: >100nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105031(4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of 125I-ET1 from human placenta cell membrane ETA receptor expressed in Baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50105031(4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of 125I-ET1 from human placenta cell membrane ETA receptor expressed in Baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed