BDBM50017698 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide::4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide::4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide(loperamide)::CHEMBL841::Imodium::LOPERAMIDE::LOPERAMIDE HYDROCHLORIDE::cid_71420::med.21724, Compound 184

SMILES: CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N

Data: 11 KI  16 IC50  2 Kd  7 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50017698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Guinea pig)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	58	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin (Bovine)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Calmodulin (Bovine)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	156	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cocaine esterase (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cocaine esterase (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orf1a protein (MERS-CoV)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cocaine esterase (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Orf1a protein (MERS-CoV)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Menin (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.268	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cocaine esterase (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		5.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nociceptin receptor (Human)	BDBM50017698 (cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair