BDBM50017702 1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-((E)-3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine(flunarizine)::CHEMBL30008::CHEMBL539027::Flunarizine::NCGC00018102::cid_6365505

SMILES: Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1

InChI Key: InChIKey=SMANXXCATUTDDT-UHFFFAOYSA-N

Data: 2 KI  22 IC50  5 Kd  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50017702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium two pore domain channel subfamily K member 2 (Bovine)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.95E+3	n/a	n/a	n/a	n/a
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Voltage-dependent N-type calcium channel subunit alpha-1B (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent T-type calcium channel subunit alpha-1H (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a
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Arachidonate 15-lipoxygenase (Pseudomonas aeruginosa)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	25
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Potassium channel subfamily K member 2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.48E+3	n/a	n/a	7.3	22
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Bile salt export pump (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1 (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 2 subunit alpha (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent T-type calcium channel subunit alpha-1I (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1G (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1I (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2J2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2J2 (Human)	BDBM50017702 (cid_6365505 | 1-(bis(4-fluorophenyl)methyl)-4-cinn...) Show SMILES Show InChI	GoogleScholar	UniChem		130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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