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BDBM50107303 CHEMBL3601003

SMILES: OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=LADPDPKGTWEYMD-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50107303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))
BDBM50107303
PNG
(CHEMBL3601003)
Show SMILES OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H15ClN2O4/c19-14-6-4-13(5-7-14)18-20-16(25-21-18)11-24-15-8-1-12(2-9-15)3-10-17(22)23/h1-2,4-9H,3,10-11H2,(H,22,23)
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Article
PubMed
n/an/an/an/a 540n/an/an/an/a



Enamine Ltd

Curated by ChEMBL


Assay Description
Agonist activity at GPR40 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin


Bioorg Med Chem Lett 25: 3105-11 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.018
BindingDB Entry DOI: 10.7270/Q26D5VS5
More data for this
Ligand-Target Pair
Free fatty acid receptor 4


(Homo sapiens (Human))
BDBM50107303
PNG
(CHEMBL3601003)
Show SMILES OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H15ClN2O4/c19-14-6-4-13(5-7-14)18-20-16(25-21-18)11-24-15-8-1-12(2-9-15)3-10-17(22)23/h1-2,4-9H,3,10-11H2,(H,22,23)
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Enamine Ltd

Curated by ChEMBL


Assay Description
Agonist activity at GPR120 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin


Bioorg Med Chem Lett 25: 3105-11 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.018
BindingDB Entry DOI: 10.7270/Q26D5VS5
More data for this
Ligand-Target Pair
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50107303
PNG
(CHEMBL3601003)
Show SMILES OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H15ClN2O4/c19-14-6-4-13(5-7-14)18-20-16(25-21-18)11-24-15-8-1-12(2-9-15)3-10-17(22)23/h1-2,4-9H,3,10-11H2,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Enamine Ltd

Curated by ChEMBL


Assay Description
Agonist activity at GPR43 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin


Bioorg Med Chem Lett 25: 3105-11 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.018
BindingDB Entry DOI: 10.7270/Q26D5VS5
More data for this
Ligand-Target Pair
Free fatty acid receptor 3


(Homo sapiens (Human))
BDBM50107303
PNG
(CHEMBL3601003)
Show SMILES OC(=O)CCc1ccc(OCc2nc(no2)-c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C18H15ClN2O4/c19-14-6-4-13(5-7-14)18-20-16(25-21-18)11-24-15-8-1-12(2-9-15)3-10-17(22)23/h1-2,4-9H,3,10-11H2,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Enamine Ltd

Curated by ChEMBL


Assay Description
Agonist activity at GPR41 (unknown origin) expressed in CHO cells by FLIPR calcium flux assay in presence of 0.1% bovine serum albumin


Bioorg Med Chem Lett 25: 3105-11 (2015)


Article DOI: 10.1016/j.bmcl.2015.06.018
BindingDB Entry DOI: 10.7270/Q26D5VS5
More data for this
Ligand-Target Pair