BDBM50108654 1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-1-yl]-3-phenylpropane::CHEMBL138458

SMILES: COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1

InChI Key: InChIKey=IJKYJDDNDXAREJ-UHFFFAOYSA-N

Data: 2 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50108654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Mouse)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 2C (Rat)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Neuromedin-K receptor (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-K receptor (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-P receptor (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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Glycine receptor subunit alpha-4 (Mouse)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Mouse)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50108654 (1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-...) Show SMILES Show InChI	GoogleScholar	UniChem		307	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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