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BDBM50110770 5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine::CHEMBL21414

SMILES: Nc1ncc(c(N)n1)-c1cccc(Cl)c1

InChI Key: InChIKey=QUIKQBNBFYGSQZ-UHFFFAOYSA-N

Data: 4 KI 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50110770
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dihydrofolate reductase (Human)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		26.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50110770 (5-(3-Chloro-phenyl)-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Show InChI	GoogleScholar	UniChem		75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair