BDBM50115587 4-(5-Chloro-1H-indol-3-yl)-2-hydroxy-4-oxo-but-2-enoic acid ethyl ester::CHEMBL108150

SMILES CCOC(=O)C(=O)CC(=O)c1c[nH]c2ccc(Cl)cc12

InChI Key InChIKey=ICGYVAPMMWDZQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115587   

TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115587(4-(5-Chloro-1H-indol-3-yl)-2-hydroxy-4-oxo-but-2-e...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute/Nih

Curated by ChEMBL
LigandPNGBDBM50115587(4-(5-Chloro-1H-indol-3-yl)-2-hydroxy-4-oxo-but-2-e...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed