BDBM50116743 3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{3-[(2-methoxy-ethylcarbamoyl)-methyl]-2-oxo-2,3-dihydro-benzoimidazol-1-yl}-piperidin-1-yl)-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide::CHEMBL75478

SMILES CCN(C\C(=N/OC)[C@H](CCN1CCC(CC1)n1c2ccccc2n(CC(=O)NCCOC)c1=O)c1ccc(Cl)c(Cl)c1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=AXBSORLKLUGMEI-OUADDPIDSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50116743   

TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Sar SP from human NK1 receptor expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]NKA from human NK2 receptor expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  945nMAssay Description:Displacement of [125I][MePhe]NKB from human NK3 receptor expressed in CHO cells membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50116743(3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{...)
Affinity DataKi:  945nMAssay Description:Binding affinity against recombinant human tachykinin receptor 3 in CHO cells using [125I]-[MePhe]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed