BDBM50118690 3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile::3-(4,4-dimethyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]oxazin-6-yl)-5-fluorobenzonitrile::CHEMBL136322

SMILES: CC1(C)OC(=O)Nc2ccc(cc12)-c1cc(F)cc(c1)C#N

InChI Key: InChIKey=KVMSWMUZFCLLFV-UHFFFAOYSA-N

Data: 9 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50118690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM50118690 (3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair