BDBM50122758 2-methyl-4-(pyridin-3-ylethynyl)thiazole::3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine::3-(2-Methyl-thiazol-4-ylethynyl)-pyridine::3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine::3-[(2-methyl-4-thiazolyl)ethynyl]pyridine::CHEMBL292065::MTEP

SMILES: Cc1nc(cs1)C#Cc1cccnc1

InChI Key: InChIKey=NRBNGHCYDWUVLC-UHFFFAOYSA-N

Data: 19 KI  21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 50122758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Glutamate receptor ionotropic, NMDA 2B (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Amine oxidase [flavin-containing] A (Mouse)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		14.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		17.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Human)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Rat)	BDBM50122758 (3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-[(...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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