BDBM50125260 2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-ethyl}-2,3,4,5-tetrahydro-benzo[c]azepin-1-one::CHEMBL273921

SMILES: Fc1ccc2n(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)c(=O)[nH]c2c1

InChI Key: InChIKey=KOTITFQGTVUMBT-UHFFFAOYSA-N

Data: 17 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50125260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2D6 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Rat)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		<3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		<5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1F (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1E (Human)	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Show InChI	GoogleScholar	UniChem		<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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