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BDBM50130462 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine::CHEMBL318105

SMILES: CN1CCC(CC1)c1c[nH]c2ccc(N)nc12

InChI Key: InChIKey=LAOHESRIMKGEEK-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130462   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50130462
PNG
(3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyrid...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(N)nc12
Show InChI InChI=1S/C13H18N4/c1-17-6-4-9(5-7-17)10-8-15-11-2-3-12(14)16-13(10)11/h2-3,8-9,15H,4-7H2,1H3,(H2,14,16)
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PC cid
PC sid
UniChem

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Article
PubMed
100n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))
BDBM50130462
PNG
(3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyrid...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(N)nc12
Show InChI InChI=1S/C13H18N4/c1-17-6-4-9(5-7-17)10-8-15-11-2-3-12(14)16-13(10)11/h2-3,8-9,15H,4-7H2,1H3,(H2,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
420n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))
BDBM50130462
PNG
(3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyrid...)
Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(N)nc12
Show InChI InChI=1S/C13H18N4/c1-17-6-4-9(5-7-17)10-8-15-11-2-3-12(14)16-13(10)11/h2-3,8-9,15H,4-7H2,1H3,(H2,14,16)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
800n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...


J Med Chem 46: 3060-71 (2003)


Article DOI: 10.1021/jm030020m
BindingDB Entry DOI: 10.7270/Q21V5DCB
More data for this
Ligand-Target Pair