BDBM50131046 8,13-Dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL85139::cid_65752::rutaecarpine

SMILES: O=c1n2CCc3c([nH]c4ccccc34)-c2nc2ccccc12

InChI Key: InChIKey=ACVGWSKVRYFWRP-UHFFFAOYSA-N

Data: 2 KI  16 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50131046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholinesterase (Horse)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A1 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear hormone receptor family member daf-12 (Caenorhabditis elegans)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Matrix metalloproteinase-9 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1B1 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50131046 (CHEMBL85139 | cid_65752 | rutaecarpine | 8,13-Dihy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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