BDBM16127 2,2 -methanediylbis(1H-benzimidazole-6-carboximidamide)::2-[(6-carbamimidoyl-1H-1,3-benzodiazol-2-yl)methyl]-1H-1,3-benzodiazole-6-carboximidamide::AIDS007118::BABIM::CHEMBL542712::CHEMBL99951

SMILES: NC(=N)c1ccc2nc(Cc3nc4ccc(cc4[nH]3)C(N)=N)[nH]c2c1

InChI Key: InChIKey=QZKOOEFIMWKZPK-UHFFFAOYSA-N

Data: 23 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 16127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dimer of Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1	-12.1	n/a	n/a	n/a	n/a	n/a	8.2	22
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Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		5	-11.2	n/a	n/a	n/a	n/a	n/a	8.2	22
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Serine protease 1 (Bovine)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		23	-10.3	n/a	n/a	n/a	n/a	n/a	8.2	22
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Serine protease 1 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		90	-9.51	n/a	n/a	n/a	n/a	n/a	8.2	22
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Serine protease 1 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30E+3	-8.00	n/a	n/a	n/a	n/a	n/a	8.1	37
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Urokinase-type plasminogen activator (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Bovine)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		4.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Bovine)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		4.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glandular kallikrein (Pig)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsin-C (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+5	-5.29	n/a	n/a	n/a	n/a	n/a	8.2	22
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Chymotrypsin-C (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		7.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chymase (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chymase (Human)	BDBM16127 (CHEMBL542712 | AIDS007118 | 2,2 -methanediylbis(1H...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+6	>-4.05	n/a	n/a	n/a	n/a	n/a	8.2	22
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