BDBM50132310 20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[24.6.1.17,14.02,6.08,13.027,32]tetratriaconta-1(33),2(6),7(34),8(13),9,11,27(32),28,30-nonaene-3,5-dione::CHEMBL103055

SMILES: CCN1CCOCCn2cc(C3=C(C(=O)NC3=O)c3cn(CCOCC1)c1ccccc31)c1ccccc21

InChI Key: InChIKey=SFDFKLDQKSPRHB-UHFFFAOYSA-N

Data: 20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50132310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2 (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C delta type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C gamma type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C epsilon type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Human)	BDBM50132310 (20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair