BDBM50132391 4-((R)-6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanol::4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanol::CHEMBL104466::RP-127963

SMILES: COc1cc2ncc(N[C@H]3CC[C@H](O)CC3)nc2cc1OC

InChI Key: InChIKey=CYVRFHRDWQAJGA-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50132391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10/8/9 (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor beta (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50132391 (RP-127963 | 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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