BDBM50134486 (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide::(R)-N-((R)-1-(4-(2-((1H-1,2,4-triazol-1-yl)methyl)phenyl)piperazin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-oxo-2-[4-(2-[1,2,4]triazol-1-ylmethyl-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL340355

SMILES: Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCN(CC2)c2ccccc2Cn2cncn2)cc1

InChI Key: InChIKey=PKHOEKKVDQTOOR-UHFFFAOYSA-N

Data: 5 KI  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50134486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
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Adrenocorticotropic hormone receptor (Mouse)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Mouse)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50134486 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair