BDBM50140543 3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-5-fluoro-4-oxo-pentanoic acid::CHEMBL23226::Z-Val-Asp-fmk

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(O)=O)C(=O)CF

InChI Key InChIKey=LYBWGROBJJXCJJ-VYIIXAMBSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50140543   

TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human recombinant caspase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-8 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against the Calpain 1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against the Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against human recombinant Caspase-3 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-7 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  5nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-9 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  20nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against the ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-6(Homo sapiens (Human))
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50:  18nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-6 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed