BDBM50143674 8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL299691

SMILES: Fc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key: InChIKey=CYDFRMLIERPUGG-UHFFFAOYSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50143674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Rat)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Rat)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		32.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		62.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50143674 (8-{2-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-8...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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