BDBM50144945 (2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methylamino-purin-9-yl)-tetrahydro-furan-3-ol::(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxy-tetrahydrofuran-3-ol::2'-O-Methyladenosine::CHEMBL73237

SMILES CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12

InChI Key InChIKey=FPUGCISOLXNPPC-IOSLPCCCSA-N

Data  3 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50144945   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes, Digestive And Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes, Digestive And Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransmembrane and immunoglobulin domain-containing 3(RAT)
National Institute Of Diabetes, Digestive And Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Santaris Pharma

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Santaris Pharma

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition HCV RNA replicationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Santaris Pharma

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human adenosine A3 receptor after 15 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Santaris Pharma

Curated by ChEMBL
LigandPNGBDBM50144945((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human adenosine A3 receptor after 15 to 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed