BDBM50147072 1-Isoquinolin-5-yl-3-phenethyl-urea::CHEMBL103842

SMILES O=C(NCCc1ccccc1)Nc1cccc2cnccc12

InChI Key InChIKey=XUHBZKHRZZSENP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147072   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50147072(1-Isoquinolin-5-yl-3-phenethyl-urea | CHEMBL103842)
Affinity DataKi:  1.44E+3nMAssay Description:Binding affinity towards human vanilloid receptor subtype 1 expressed in HEK293 cell membrane using [3H]-RTX as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50147072(1-Isoquinolin-5-yl-3-phenethyl-urea | CHEMBL103842)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonistic activity towards human vanilloid receptor subtype 1 expressed in HEK293 cell membrane, as inhibition of agonist-induced intracellular [C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed