BDBM50151511 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide::CHEMBL433750::N-((R)-1-(4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpiperidin-1-yl)-3-(4-chlorophenyl)-1-oxopropan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

SMILES: Clc1ccc(C[C@@H](NC(=O)C2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key: InChIKey=HLCHESOMJVGDSJ-UHFFFAOYSA-N

Data: 15 KI  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50151511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.610	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.820	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.710	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50151511 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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