BDBM50151593 8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL182703
SMILES: Clc1cc(cc2c1NC(=O)NC21CCCCC1)-c1ccccc1
InChI Key: InChIKey=OFWGHMAISKOSQV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50151593 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C
(Human) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 6.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Human) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Human) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | >1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Human) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Mouse) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Mouse) | BDBM50151593
 (8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...) | GoogleScholar
| UniChem
| | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |