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BDBM50151593 8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL182703

SMILES: Clc1cc(cc2c1NC(=O)NC21CCCCC1)-c1ccccc1

InChI Key: InChIKey=OFWGHMAISKOSQV-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50151593   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C


(Human)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 3.26E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase


(Human)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 6.98E+4n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A


(Human)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 10n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A


(Human)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a>1.01E+5n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Human)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 1.42E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta


(Mouse)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 16n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta


(Mouse)
BDBM50151593
PNG
(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
GoogleScholar
UniChem
n/an/a 1.42E+3n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair