BDBM50151623 8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL185208
SMILES: Clc1cc(cc2c1NC(=O)NC21CCCCC1)-c1ccncc1
InChI Key: InChIKey=FMESWXOJQKIMDP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50151623 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cGMP-specific 3',5'-cyclic phosphodiesterase
(Human) | BDBM50151623
(8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-...) | GoogleScholar
| UniChem
| | n/a | n/a | 9.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C
(Human) | BDBM50151623
(8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-...) | GoogleScholar
| UniChem
| | n/a | n/a | 3.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
(Human) | BDBM50151623
(8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-...) | GoogleScholar
| UniChem
| | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
(Human) | BDBM50151623
(8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-...) | GoogleScholar
| UniChem
| | n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Human) | BDBM50151623
(8''-chloro-6''-(4-pyridyl)spiro[cyclohexane-1,4''-...) | GoogleScholar
| UniChem
| | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
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