BDBM50153250 5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid::5,6-dihydroxy-2-(2-thienyl)pyrimidine-4-carboxylic Acid::5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylic acid::CHEMBL181653

SMILES: OC(=O)c1nc([nH]c(=O)c1O)-c1cccs1

InChI Key: InChIKey=SSOGKSFNCMYOPA-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50153250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tripartite terminase subunit 3 (HHV-5)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Flap endonuclease 1 (Human)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Deoxyribonuclease-1 (Human)	BDBM50153250 (5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair