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BDBM50153254 5,6-dihydroxy-1-methyl-2-thiophen-2-yl-pyrimidine-4-carboxylic acid::5-Hydroxy-1-methyl-6-oxo-2-thiophen-2-yl-1,6-dihydro-pyrimidine-4-carboxylic acid::5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dihydropyrimidine-4-carboxylic acid::CHEMBL366051
SMILES: Cn1c(nc(C(O)=O)c(O)c1=O)-c1cccs1
InChI Key: InChIKey=CWHZCSASLVDDDM-UHFFFAOYSA-N
Data: 6 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| RNA-directed RNA polymerase (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Flap endonuclease 1 (Human) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | 8.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Deoxyribonuclease-1 (Human) | BDBM50153254![]() (5-hydroxy-1-methyl-6-oxo-2-(thiophen-2-yl)-1,6-dih...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||