BDBM50155358 7-Chloro-4-(2-cyclopentyl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide::CHEMBL185438

SMILES Cc1cc(cc(C)c1C)-c1c(OCCC2CCCC2)c2cc(C(=O)Nc3cnsn3)c(Cl)cc2[nH]c1=O

InChI Key InChIKey=ASVLYALZPZGNFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155358   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155358(7-Chloro-4-(2-cyclopentyl-ethoxy)-2-oxo-3-(3,4,5-t...)
Affinity DataIC50:  243nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor expressed in CHO cells was determined by using [125I]-buserelin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155358(7-Chloro-4-(2-cyclopentyl-ethoxy)-2-oxo-3-(3,4,5-t...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells expressing GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed