BDBM50155967 4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amino)-6-methyl-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one::CHEMBL186252

SMILES CCCCN(CC)c1cc(C)nc2N(CC(=O)Nc12)c1ccc(cc1Br)C(C)C

InChI Key InChIKey=DGJZQKKOYYDIGL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155967   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50155967(4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amin...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRF1 receptor expressed in HEK293T cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155967(4-(2-Bromo-4-isopropyl-phenyl)-8-(butyl-ethyl-amin...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of [125I]-ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed