BDBM50159343 CHEMBL3787394
SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CC(C1)Oc1ccc(CN2CC3(COC3)C2)cc1
InChI Key InChIKey=BKKPIQPFRAPEAY-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50159343
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+4nMAssay Description:Antagonist activity at human MCHR2 expressed in CHO cells after 60 to 75 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair