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BDBM50168595 4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan-3-ylamine::CHEMBL187339

SMILES: CCn1c(nc2cc(F)ccc12)-c1nonc1N

InChI Key: InChIKey=NUTGASVSNUNYIX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168595   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 5


(Homo sapiens (Human))
BDBM50168595
PNG
(4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan...)
Show SMILES CCn1c(nc2cc(F)ccc12)-c1nonc1N
Show InChI InChI=1S/C11H10FN5O/c1-2-17-8-4-3-6(12)5-7(8)14-11(17)9-10(13)16-18-15-9/h3-5H,2H2,1H3,(H2,13,16)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 38n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory concentration exhibited towards MSK-1


Bioorg Med Chem Lett 15: 3402-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.021
BindingDB Entry DOI: 10.7270/Q2Z037P9
More data for this
Ligand-Target Pair