BDBM50169445 (1S,4R,6S)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-carboxylic acid [(R)-2-(4-tert-butylcarbamoyl-4-cyclohexyl-piperidin-1-yl)-1-(4-fluoro-benzyl)-2-oxo-ethyl]-amide::CHEMBL429387

SMILES CN1C[C@@H]2CC[C@H]1[C@H](C2)C(=O)N[C@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCCC1)C(=O)NC(C)(C)C

InChI Key InChIKey=ARFBDECCXOFCBN-KULMNKMISA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169445   

TargetMelanocortin receptor 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169445((1S,4R,6S)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataIC50:  410nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 3 by displacement of [125I]NDP-alpha-MSH from the human receptors exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169445((1S,4R,6S)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataIC50:  6nMAssay Description:Inhibition concentration (binding affinity) against human melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169445((1S,4R,6S)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataIC50:  1.08E+3nMAssay Description:Effective concentration (binding affinity) exhibited against human melanocortin receptor 5 by radio labeled ligand assay (Displacement of [125I]NDP-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169445((1S,4R,6S)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-c...)
Affinity DataEC50:  34nMAssay Description:Inhibition concentration (binding affinity) exhibited against human melanocortin receptor 4 by radio labeled ligand assay (Displacement of [125I]-NDP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed