BDBM50175461 3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-methyl-5,6,7,8-tetrahydro-3H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-one::CHEMBL370110

SMILES: CN1CCc2c(C1)sc1ncn(CCN3CCN(CC3)c3cncc4ccccc34)c(=O)c21

InChI Key: InChIKey=HIBUHKNMTZCDMF-UHFFFAOYSA-N

Data: 10 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50175461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		>10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		16.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1B (Rat)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		33.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50175461 (3-[2-(4-isoquinolin-4-yl-piperazin-1-yl)-ethyl]-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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