BDBM50044080 2-Amino-5-[1-(3,5-di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-thiazol-4-one; compound with methanesulfonic acid::CHEMBL109745::CHEMBL196996::CHEMBL275835::Darbufelone mesylate

SMILES: CC(C)(C)c1cc(C=C2SC(N)=NC2=O)cc(c1O)C(C)(C)C

InChI Key: InChIKey=AKTXOQVMWSFEBQ-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50044080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Human)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Mouse)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Rabbit)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Rabbit)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1/2 (Human)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50044080 (CHEMBL196996 | 2-Amino-5-[1-(3,5-di-tert-butyl-4-h...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair