BDBM50175522 1-{2-[3-((S)-3,4-Dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl}-4-phenyl-piperidine-4-carboxylic acid amide::CHEMBL372587::MDL 105,212 (R)-enantiomer

SMILES: COc1cc(cc(OC)c1OC)C(=O)N1CC[C@](CCN2CCC(CC2)(C(N)=O)c2ccccc2)(C1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=WZMVQZJKOVPVGZ-UHFFFAOYSA-N

Data: 7 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50175522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Substance-K receptor (Human)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-P receptor (Human)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-P receptor (Guinea pig)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		2.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-P receptor (Human)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		3.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-K receptor (Golden hamster)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		6.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-K receptor (Human)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-K receptor (Bovine)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		8.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Guinea pig)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Substance-P receptor (Rat)	BDBM50175522 (CHEMBL372587 | MDL 105,212 (R)-enantiomer | 1-{2-[...) Show SMILES Show InChI	GoogleScholar	UniChem		408	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair