BDBM50176521 5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-carboxylic acid [1,3,4]thiadiazol-2-ylamide::CHEMBL200906

SMILES: CN1C(=O)C(C(=O)Nc2nncs2)c2cc3occc3cc12

InChI Key: InChIKey=OQMLSKSSPKAKJQ-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50176521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (Human)	BDBM50176521 (5-methyl-6-oxo-6,7-dihydro-5H-furo[2,3-f]indole-7-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair