BDBM50180054 CHEMBL199824::[O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione

SMILES: COc1ccc2cccc(N3CCN(CCCCn4ncc(=O)n(C)c4=O)CC3)c2c1

InChI Key: InChIKey=GKTQBPYMIGXPKG-UHFFFAOYSA-N

Data: 42 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 44 hits for monomerid = 50180054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0100	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 7 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 6 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 5A (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		476	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		6.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		6.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cannabinoid receptor 1 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a/A2b (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-3 adrenergic receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vasopressin V1a/V1b receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vasopressin V2 receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2a (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chromaffin granule amine transporter (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A3 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cannabinoid receptor 2 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tumor necrosis factor receptor superfamily member 16 (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Synaptic vesicular amine transporter (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50180054 ([O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)pi...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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