BDBM50181295 5-(3-((S)-2-(3-hydroxy-4-(naphthalen-2-yl)butyl)-5-oxopyrrolidin-1-yl)propyl)thiophene-2-carboxylic acid::CHEMBL208410

SMILES OC(CC[C@H]1CCC(=O)N1CCCc1ccc(s1)C(O)=O)Cc1ccc2ccccc2c1

InChI Key InChIKey=XMZZINOBVHKJPS-HMTLIYDFSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181295   

TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181295(5-(3-((S)-2-(3-hydroxy-4-(naphthalen-2-yl)butyl)-5...)
Affinity DataEC50:  500nMAssay Description:Activity at rat EP4 transfected in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181295(5-(3-((S)-2-(3-hydroxy-4-(naphthalen-2-yl)butyl)-5...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181295(5-(3-((S)-2-(3-hydroxy-4-(naphthalen-2-yl)butyl)-5...)
Affinity DataIC50:  65nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed