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BDBM50182464 2',4-difluoro-5'-[3-(trifluoromethyl)imidazo[1,2-b][1,2,4]triazin-7-yl]biphenyl-2-carbonitrile::CHEMBL427207
SMILES: Fc1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnc2nc(cnn12)C(F)(F)F
InChI Key: InChIKey=BCLNCXBDWXPRAH-UHFFFAOYSA-N
Data: 2 KI
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Human) | BDBM50182464![]() (2',4-difluoro-5'-[3-(trifluoromethyl)imidazo[1,2-b...) | GoogleScholar | UniChem | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| GABA-A receptor; alpha-2/beta-3/gamma-2 (Human) | BDBM50182464![]() (2',4-difluoro-5'-[3-(trifluoromethyl)imidazo[1,2-b...) | GoogleScholar | UniChem | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||