BDBM50184436 2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine::CHEMBL204098

SMILES CN1CCc2ccccc2Cc2cc(N)c(O)cc2CC1

InChI Key InChIKey=MUNUWDYLOYQPCC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184436   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]SCH 23390 from D1 dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  20.9nMAssay Description:Inhibition of D1 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  26.1nMAssay Description:Inhibition of D2L dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  37.3nMAssay Description:Displacement of [3H]spiperone from D2L dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  39.5nMAssay Description:Inhibition of D5 dopamine receptor in HEK 293 cells by intracellular calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-UniversitäT Jena

Curated by ChEMBL
LigandPNGBDBM50184436(2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrod...)
Affinity DataKi:  227nMAssay Description:Binding affinity to D5 dopamine receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed