BDBM50184484 5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-1-[3-(tetrahydro-pyran-2-yloxy)-propyl]-1H-benzoimidazole::CHEMBL204158

SMILES: C(COC1CCCCO1)Cn1cnc2cc(ccc12)-c1c2CCCn2nc1-c1ccccn1

InChI Key: InChIKey=VTPAYYPWGCIXCD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50184484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM50184484 (5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 20 (Human)	BDBM50184484 (5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50184484 (5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
TGF-beta receptor type-2 (Human)	BDBM50184484 (5-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyr...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair