BDBM50185061 (4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-7-methylazepan-2-one::CHEMBL209407

SMILES C[C@@H](O[C@H]1C[C@@H](C)NC(=O)C[C@@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JUCZGNXHCDAERA-RDPGKOORSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185061   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185061((4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataKi:  8.50E+3nMAssay Description:Displacement of labeled MK-499 from cloned hERG channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185061((4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)pheny...)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [125I] labeled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed