BDBM50185354 3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopropyl]indole-3,5-dicarboxylate::CHEMBL443834

SMILES CCCCCCCCCCOc1ccc(OCC(=O)Cn2cc(C(=O)OC)c3cc(ccc23)C(O)=O)cc1

InChI Key InChIKey=NXDZVUAKVFVDSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50185354   

TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185354(3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of cPLA2-alpha activity assessed by TPA-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185354(3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...)
Affinity DataIC50:  570nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of MüNster

Curated by ChEMBL
LigandPNGBDBM50185354(3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopro...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human isolated cPLA2alpha by vescicle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed