BDBM50185474 (+)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::(-)-4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::(-)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::4-(3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one::4-[3-(4-Chloro-phenyl)-3-hydroxy-pyrrolidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL150161

SMILES: OC1(CCN(CCCC(=O)c2ccc(F)cc2)C1)c1ccc(Cl)cc1

InChI Key: InChIKey=BETHXCLHMRGYBW-UHFFFAOYSA-N

Data: 41 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50185474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		7.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		7.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		241	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(4) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histamine H1 receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		489	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		489	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		722	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		722	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2C (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Alpha-2A adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50185474 ((+)-4-{3-(4-chlorophenyl)-3-hydroxypyrrolidin-1-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		4.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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