BDBM50185974 CHEMBL205964::N-(3-{4-[4-(tert-butylcarbamoyl)benzyl]piperidin-1-yl}propyl)-N-(3,4-dichlorophenyl)-1-(methylsulfonyl)piperidine-4-carboxamide

SMILES CC(C)(C)NC(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(CC3)S(C)(=O)=O)c3ccc(Cl)c(Cl)c3)CC2)cc1

InChI Key InChIKey=AFKBGLZHUWDUOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185974   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185974(CHEMBL205964 | N-(3-{4-[4-(tert-butylcarbamoyl)ben...)
Affinity DataIC50:  12nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185974(CHEMBL205964 | N-(3-{4-[4-(tert-butylcarbamoyl)ben...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed