BDBM50187997 1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::CHEMBL213504

SMILES: Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3)c12

InChI Key: InChIKey=KIXJPVWFCZCXOL-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50187997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Human)	BDBM50187997 (1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair