BDBM50189805 CHEMBL445067::N-(2-(4-methoxyphenyl)-1-oxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)-2,2-diphenylacetamide

SMILES COc1ccc(cc1)-n1nc2c(NC(=O)C(c3ccccc3)c3ccccc3)nc3ccccc3n2c1=O

InChI Key InChIKey=BVZYBSKEJKEJOJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50189805   

TargetAdenosine receptor A1(BOVINE)
Università

Curated by ChEMBL
LigandPNGBDBM50189805(CHEMBL445067 | N-(2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in bovine brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50189805(CHEMBL445067 | N-(2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataKi:  44nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50189805(CHEMBL445067 | N-(2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of NECA-stimulated cAMP level in CHO cells transfected with human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50189805(CHEMBL445067 | N-(2-(4-methoxyphenyl)-1-oxo-1,2-di...)
Affinity DataIC50:  215nMAssay Description:Antagonist activity against Cl-IB-MECA inhibited cAMP level in CHO cells transfected with human A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed